Each one of my series are intended to be read on their own. If you’ve stumbled across one that looks interesting, you should be able to start there and enjoy it.
If you’d like to get the “core story” of the Descentverse, I recommend reading: The Descent Series, The Cain Chronicles, The Ascension Series, War of the Alphas, and The Mage Craft Series.
If you’re interested in tackling the entire body of my work, here is a flow chart that illustrates how all the series fit together.
(Please note: Genesis is an event that occurs within the books, and not a series. You’ll understand once you’ve read to that point.)